New nanoparticles target fat absorption in gut

Researchers have introduced a groundbreaking method to combat obesity: targeting fat absorption in the small intestine using a novel nanoparticle delivery system.

This innovative approach, designed to transport therapeutic molecules directly to the digestive tract, shows great promise in preventing diet-induced obesity. Previous research on fat metabolism has struggled to find an effective way to block fat absorption, but this study offers a fresh and promising solution.

“For years, researchers have studied fat metabolism, but finding an effective way to block fat absorption has been difficult,” explained Dr. Wentao Shao, the study’s lead researcher.

“While most strategies focus on reducing dietary fat intake, our approach targets the body’s fat absorption process directly.”

Targeting intestinal fat absorption

The study focuses on the enzyme Sterol O-acyltransferase 2 (SOAT2), which is key to fat absorption within the small intestine. By inhibiting this enzyme…

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